Monthly Archives: December 2014

Report on Dental Laboratories Market – Industry Analysis and Forecast up to 2019

Dental laboratories perform technical procedures related to dental treatment without any direct involvement of the dentists and patients. These laboratories manufacture and customize variety of dental products like dentures, bridges, crowns and others. Dental laboratories comprises of various dental technicians like laboratory technicians, dental technologist, dental ceramics and others. These laboratories have strategic contracts with patients and many pharmaceutical and other industries that purchase their dental materials.

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Increasing population that uses dental services will drive the growth of dental laboratories market. In addition, introduction of advanced technologies such as cosmetic procedures and tooth implants will drive the growth of dental laboratories market. Technological advancements allow operators to cut down manufacturing cost that will further augment the growth of dental laboratories market. Furthermore, rising geriatric population globally that demands the services from dental industry will drive the growth of dental laboratories market. Incorporation of computer aided design (CAD) and computer aided manufacturing (CAM) further stimulates the demand of dental services and hence drives the market growth of dental laboratories. In addition, the market of dental laboratories is witnessing positive growth due to increasing demand for better dental aesthetics, rising per capita spending across developed countries and healthcare awareness among patient population. However, economic pressure will pose significant difficulties for the patients to afford high priced dental surgeries that restrain the market of dental laboratories.

Geographically, North America is considered to be the largest market of dental laboratories owing to increasing efforts of various domiciled organizations for the development of dental laboratories field. For example, National Association of Dental Laboratories (NADL) is a national trade association based in North America. This association is engaged in businesses involved in commercial dental laboratories. In addition, increasing number of dental problems in North America ultimately drives the growth of dental laboratories market. For example, according to American Cancer Society, in North America approximately 42,440 new cases were reported for oral cancer in 2014 and the number is increasing every year. This factor would increase the demand of dental services and hence drives the growth of dental laboratories market. Europe is considered as the second largest market of dental laboratories. The growth is mainly attributed to widespread availability of new treatment options coupled with introduction of advanced techniques for the treatment of dental problems such as gum diseases, tooth erosion and oral cancer will drive the growth of dental laboratories market. In addition, rising aging population will further boost the growth of dental laboratories market in Europe. According to the European Commission (Eurostat) in 2013, around 17.8% of the European population were aged 65 years and above. Thus, aging population and advancement in technologies would increase the uptake of dental services in Europe and thus drives the market growth of dental laboratories. In addition, Asia-Pacific region is the emerging market for dental laboratories because of rising awareness about oral healthcare among the people. In addition, rising per capita income and increasing spending of people on dental surgeries in Asia-Pacific region will further stimulate the growth of dental laboratories market.

Some of the market players in this industry segment are Attenborough iDent Dental Lab, Dental, 1st Dental Laboratories Plc., Knight Dental Design, Dental Services Group, Champlain Dental Laboratory, Southern Craft Dental Laboratory, Lord’s Dental Studio, National Dentex Corp., Utah Valley Dental Lab and others.

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Global Early Toxicity Testing Market – Industry Segment and Forecast, 2013 – 2019

Toxicity is an extent to which a particular substance can damage the living organism; it is important parameter to be evaluated during all stages of drug development. Toxicity is one of the major reasons for failure of drug development and rejection of drug candidate. Toxicity can be because of dosage, form, half life and other parameters of drug. Since long time toxicity is measured at the later stage of the drug development process but considering higher rejection rate of drug in recent years citing high toxicity level and cost impact of later stage failure, companies started early toxicity testing and taken measures accordingly to reduce the attrition rate in drug discovery.

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Early toxicity testing can be of three types namely in vivo, in vitro and in silico. In vivo toxicity testing is performed on living animals, in in vitro technique testing is performed in laboratories using biochemical assays and cellular assays without animals whereas in in silico technique testing is done by data analysis on computer with the help of data mining and data modeling tools. Out of all these techniques, there are significant advancements happened in in vivo technique; while other two techniques are still in development stage. According to industry leader, cost of drug those get rejected because of late toxicity is 40% of overall drug development spending, where there is around USD 50 billion spend on drug development put together. Many organizations which are working towards environment and animal protection are opposing in vivo approach, and are pressurizing governments to make companies opt for in silico approach. Several initiatives such as FDA’s Critical Path Initiative and the European Union’s Seventh Research Framework Programme are aimed at improving toxicity evaluation process during drug development stages.

Therefore in coming years there may be considerable shift of paradigm from in vivo to in vitro and in silico. There are some studies conducted for usage of nanoparticles in toxicological testing, along with this developments are also in progress for producing 3 dimensional human tissues for toxicity testing. Organovo is one of the players focused on replacing animal testing and biological assays by producing model of human liver. This model mimics the form and functions of human liver and therefore can be used for toxicological testing.

Early toxicity testing market can be segmented in various categories such as on the basis of regional geography, approach of technique and according to market share by major companies. According to technical approach early toxicity testing market is segmented in in vivo, in vitro and in silico, among all these in vivo market contributing highest followed by in vitro and in silico. Pharmaceutical companies, chemical companies and companies related to food products are main customers for early toxicity detection testing players.

Some of the market players in this industry segment are Accelrys, BD Biosciences, Beckman Coulter, Inc., Charles River Laboratories, Gene Logic, Invitrogen, Covance, IDBS, Thermo Fisher.

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Global Surgical Incision Closure Market – Industry Segment, Trends and Forecast, 2013 – 2019

Effective closure of surgical incisions plays a crucial role in post-surgical process to regain normal anatomical functions and maintain the integrity of tissues. Thus, the primary objective of surgical incision closure devices is to stop bleeding i.e. hemostasis and to close or seal the wound both externally and internally. Failure to close surgical incisions effectively can lead to severe medical complications such as infection and scarring. The commonly involved technique in conventional surgical incision closure is the use of surgical sutures for stitching together the incised skin edges. But modern methods introduced are more advanced and convenient; to mention some of the advanced methods – use of adhesives, hemostats, medical staples and sealants.

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The commonly used surgical incision closure products include:

  • Surgical sutures
  • Absorbable
  • Non-absorbable
  • Hemostats
  • Collagen based
  • Oxidized regenerated cellulose based
  • Thrombin based
  • Ligating clips
  • Medical staples
  • Tissue sealants
  • External
  • Internal

Technologically advanced surgical incision closure devices, for instance, tissue sealants, hemostats and similar other devices play an important role in driving the market due to benefits offered such as fewer traumas, reduced risk of infections, better cosmetic outcomes and reduced recovery time. Also, there are many surgical incision closure products in the pipeline that are exploring usage of alternative materials, for example, titanium suture needles to replace medical grade stainless steel needles used for suturing among others; thus high investment in R&D is likely to lead the development and supply of newer, effective surgical incision closure products. This in turn is likely to drive the demand for surgical incision closure products in the future. However, the growth of such devices could be hindered in the future due to rise in preference for minimally invasive surgical procedures among patients.

North America followed by Europe are expected to be the largest markets owing to a high consumer base of aesthetic surgeries, knee replacement surgeries, hip replacement surgeries and spinal fusions. Asia-Pacific is estimated to register a remarkable growth because of few notable reasons such as improvements in healthcare infrastructure, increased access to healthcare services, establishment of new hospitals and diagnostic centers and rising spends in the healthcare segment.

Few of the leading companies involved in the development, manufacturing and distribution of surgical incision closure devices are 3M HealthCare, Axya Medical, Inc., Baxter International Inc., BTG International, Inc., Covidien Ltd., CryoLife, Inc., Ethicon Inc., Genzyme Biosurgery, Inc, Henkel Loctite Corporation/Henkel Group, Smith & Nephew PLC, Tyco Healthcare/Tyco International among others.

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Global Cardiac Assist Devices Industry Segment and Forecast, 2013 – 2019

Cardiac Assist Devices (CAD) are type of mechanical pumps that work along with the heart to improve its pumping efficiency and maintain the optimum blood flow throughout the body. Cardiac Assist Devices can be segmented in three types ventricular assist devices, intra-aortic balloon pumps (IABPs) and total artificial heart. Ventricular assist device (VAD) is a mechanical pump which takes blood from a lower chamber of the heart and pumps it to the body and vital organs. Ventricular devices are of two types right ventricular assist device (RVAD), left ventricular assist device (LVAD) and if both the ventricular assist devices are used they’re known as biventricular assist device (BIVAD). Intra-aortic balloon pump is a type of CAD device which increases myocardial oxygen perfusion and cardiac output at the same time. Total artificial heart is a device which replaces the lower chambers of heart and recovers failing heart by performing all functions of a normal heart.

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Cardiac assist devices market is expected to be driven by global aging population and increase in cardiovascular diseases. A another factor responsible for market growth of this market is lack of donor hearts for transplantation leading to increase in cardiac assist devices implantations in patients with severe heart complications. In future technological advancements and more efficient and minimally invasive devices are expected to drive the market.

North America is the leading markets for Cardiac Assist Devices (CAD) because of highest heart failure cases diagnosed, technological development, high patient awareness and reimbursement coverage for CAD implantation procedures. Europe is the second largest market following North Amercia with second largest highest prevalence for cardiac diseases and increase in population exceeding 60 – 65 years of age group. Asia Pacific and Rest of the World are the regions including China, India, Brazil, Russia and South Africa has significantly large number of underserved patients suffering with cardiac diseases hence represented as future attractive markets for CAD.

Some of the key players of Cardiac Assist Devices (CAD) market are Berlin Herat GmbH, ABIOMED, Inc., MAQUET GmbH & Co. KG, Thoratec Corporation, Teleflex Incorporated, HeartWare International, Inc. and SynCardia Systems, Inc.

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About Us

Transparency Market Research is a market intelligence company providing global business information reports and services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insight for thousands of decision makers.

Contact:

Transparency Market Research

90 State Street,
Suite 700,
Albany
NY – 12207
United States
Tel: +1-518-618-1030

USA – Canada Toll Free 866-552-3453

Email: sales@transparencymarketresearch.com

Website: http://www.transparencymarketresearch.com/

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