Vena Cava Clips and Filters Market Analysis by Recent Trends, and Growth Forecast 2025

Scientists need to perform intensive research and study to design a vaccine against particular microbes. This vaccine is based on the fundamental information such as how it infects the human or animal cell and what is the immune reaction of the infected cell. Researchers have developed different types of vaccines such as live attenuated vaccines, subunit vaccines, inactivated vaccines, conjugate vaccines, toxoid vaccines, DNA vaccines, and recombinant vector vaccines.

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In recent years, the recombinant DNA technology has been used to generate new vaccines. This technology has helped scientists to develop recombinant vector vaccines against various bacterial and viral diseases. Recombinant vector vaccines are similar to DNA vaccines; however, these consist of an attenuated viral particle or bacterium as a vector.

Viruses adsorb on to a cell and inject their genetic material into them. Scientists have taken advantage of this viral nature and developed recombinant viral vector vaccines using attenuated virus as a carrier of the genetic material into the host cell. Recombinant vector vaccines have several advantages over other traditional vaccines. These vaccines closely mimic a natural infection caused by a particular microbe, thereby generating a good immune response against it. Recombinant vector vaccine strategy enables triggering of T- lymphocyte, and antigens, are thus presented to T- cell lymphocytes which generates a strong cell mediated immune response in the body against that particular antigen or microbe.

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Moreover, it reduces need of repeat dosage to treat a particular disease. Attenuated bacterium can also be used as an efficient vector to generate recombinant vector vaccines. In this case, genetic material is inserted into the bacterial vector, causing the bacteria to express the antigens of other microorganism onto its surface, generating an immune response. Strong research is being carried out to develop recombinant vector vaccines for rabies, HIV, and measles. Currently, adenovirus vectors, poxvirus vectors, and alphavirus vectors are extensively studied and used to prepare vaccines.

Rapid development in molecular biology and genetic engineering is the key driver of the global recombinant vector vaccine market. The market is expected to show a rapid growth during the forecast period. However, substantial number of pharmaceutical challenges associated with the development of recombinant vector vaccines and stringent regulatory norms laid by the regulatory bodies is likely to restrain the market.

The global recombinant vector vaccines market can be segmented based on type of vector, disease type, and region. In terms of type of vector, the market can be bifurcated into recombinant viral vector vaccines and recombinant bacterial vector vaccines. The recombinant viral vector vaccines segment holds the maximum share of the market. Based on disease type, the market can be segmented into vector vaccines used to treat various viral and bacterial infections. Recombinant vector vaccines are being developed to treat cancer.

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Geographically, the global recombinant vector vaccines market can be segmented into Europe, Asia Pacific, Latin America, North America, and Middle East & Africa. North America held a major share in 2016, owing to rise in technology advancements in molecular biology and genetic engineering. Increasing awareness, government initiatives, and availability of vector vaccines are expected to boost the growth of the market in Asia Pacific. The recombinant vector vaccines market in Europe is anticipated to grow during the forecast period owing to technological developments and increasing prevalence of infectious diseases.

Key players in the global recombinant vector vaccines market include Sanofi, Pfizer, Inc., Novartis AG, Neuron Biotech, Merck and Company, GlaxoSmithKline plc, CSL Limited, Biological E, and Bharat Biotech.

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Condylar Plate Fixation Market Boosting the Healthcare Industry Worldwide 2017 – 2025

A molecular weight marker is used during electrophoresis on the gel, to identify the approximate size of the molecule. On the gel matrix, the principle used to identify the molecular weight is that the migration rate is inversely proportional to the molecular weight. Therefore, the effective logarithmic scale formed on the gel is used to estimate the size and weight of the unknown protein or DNA or RNA, provided that the molecular weight of the marker is already known. Molecular weight markers can run on either polyacrylamide gel or agarose gel. Before the commencement of the gel electrophoresis, the molecular weight markers are loaded in the lane adjacent to the sample lane, for easy determination of the weight and size of the unknown samples like RNA or DNA or protein.

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The major drivers for the global molecular weight marker market are increasing number of biotechnology patents and the expenses on research and development. Also, increased public sector funding for basic research in biotechnology and pharmaceutical companies is anticipated to drive the demand for molecular weight markers significantly. There is remarkable opportunity for the molecular weight markers market as biotechnology laboratories, life science & pharmaceutical companies and other end users are constantly utilizing separation and analysis technology. Currently, there are cutting edge expansions of profiling applications which are expected to continuously boost demand for molecular weight markers. Genomics application is augmenting the growth of the global molecular weight marker market.

Based on product type, the market for molecular weight markers can be segmented as RNA markers, protein markers, and DNA markers. The largest share of the market is held by the segment of DNA markers. Based on application type, the market can be segmented into nucleic acid applications and protein applications. Nucleic acid applications can further be classified as northern blotting, polymerase chain reaction (PCR), molecular cloning, southern blotting, sequencing and others. Protein applications can further be classified as gel extraction, Western blotting and others. The segment of protein applications is expected to expand during the forecast period 2017 to 2025, while a larger share of the market is held by the nucleic acid applications segment. Based on end user type, the market for molecular weight markers can be segmented into clinical research organizations, pharmaceutical companies, academic institutes, and others.

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Geographically, the market for global molecular weight markers can be segmented into Asia Pacific, North America, Europe, Latin America and the Middle East & Africa. North America holds the largest share in the global molecular weight marker market. In 2012, North America accounted for around 40% of global research and development expenses. Asia Pacific countries have represented significant increase in the percentage expenditure on development and research & specifically on molecular biology from 2012 onwards. In the coming years, Asia Pacific is expected to grow at the fastest growth rate as it accounted for 30% of the global research and development expenses in 2012.

Globally, the leading companies in the market of molecular weight markers are Thermo Fisher Scientific Inc., F Hoffmann-La Roche AG, Sigma-Aldrich, Agilent Technologies, QIAGEN, Affymetrix, Inc., Bio-Rad Laboratories, Takara Bio Inc., New England Biolabs, and Promega Corporation among others. The growth of the market for molecular weight markers is driven by partnerships between biotechnology companies, pharmaceutical companies, and academic research institutes.

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Angiotensin II Inhibitors with Calcium Channel Blockers Market Size, Growth, Trends and 2025 Forecast Report

Global Glycobiology Market: Snapshot 

The world glycobiology market is envisioned to sense a strong lead in the biotechnology sector with the mutual advantage of glycobiology and proteomics proliferating their applications in different fields. Due to the capacious overlap and interdependency of both glycobiology and proteomics markets on the part of instrument sections, the global market could gain a sound impetus from the episode.

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With regard to segmentation, the global glycobiology market could be analyzed on the basis of product, application, and end user. The geographical segmentation can provide an outlook of the key regions that practice the various applications of glycobiology.

The authors of the report have taken to thoroughgoing primary and secondary research to provide a reliable platform for both new entrants and established players to make intelligent decisions. Besides this, the analysts have provided critical data on the forecast of future trends and present market size. 

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Global Glycobiology Market: Trends 

The international glycobiology market is foreseen to be motivated by the enlarging research and development spending on the part of biotechnology and pharmaceutical organizations. One of the most influential motive powers for the growth of the global market is the heightening private and government funding initiated for forwarding research activities related to proteomics and glycomics.

The drug discovery and development division by application was anticipated to hold a gargantuan share in the world glycobiology market in 2016. The advancement of this possible segment could be accredited to the rise in the evolution of unconventional therapies and drugs through thorough research and development. Other segments such as immunology, oncology, and diagnostics could be listed under the application category.

Out of the many probable product type segments, enzymes are predicted to register a higher CAGR and growth on the back of their extensive applications in drug discovery and research and development operations. While they can be further segregated as sialyltransferases, neuraminidases, glycosyltransferases, and glycosidases, the other glycobiology products could be reagents, kits, and instruments.

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If the end users are concerned, a larger share of the global glycobiology market was expected to be secured by academic research institutes in 2016. The success of this end-user segment could be attributed to the strong private and government support offered through funding. Other end users such as contract research organizations and pharmaceutical and biotechnology firms are foretold to stay in the run. 

Global Glycobiology Market: Geography 

Although the world glycobiology market could be geographically divided into North America, Europe, Asia Pacific, and Rest of the World, Asia Pacific is envisaged to outshine while riding on a sharp CAGR. Much of the demand for glycobiology in Asia Pacific could be ascribed to the uprising significance of companion diagnostics, maturing want for customized medicine, and escalating research and development commercialization by biotech and pharma firms.

North America may not lag behind in terms of growth, mainly due to the increasing incidences of herpes, AIDS, cancer, and other infectious and chronic illnesses. The sedentary lifestyle and multiplying geriatric population in this region is deemed to be responsible for the prevalence of such diseases. Moreover, citizens are being able to access well-assembled reimbursement programs and afford expensive medication, which is expected to further push the rise of North America. 

Global Glycobiology Market: Competition 

The report presented here for the perusal of the buyers could include an unfathomable study of the competitive landscape along with the future trends of the glycobiology industry. Some of the epoch-making players of the world glycobiology market could be Waters Corporation, Thermo Fisher Scientific, Takara Bio, Inc., Merck KGaA, Shimadzu Corporation, ProZyme, Inc., New England Biolabs, Danaher Corporation, Bruker Corporation, and Agilent Technologies.

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Pharmaceutical Granulation Equipment Market Research Key Players, Industry Overview and forecasts to 2025

Granulation is the process of binding small particles into larger permanent masses, in which the original particles can still be identified. The process is intended to improve manufacturing processes by increasing flow of the material from the hopper during compression of the tablets, improving packaging of the dry suspension granules in the final containers, and creating surface for coating of drugs in sustained and extended release dosage forms. Two types of granulation processes such as dry granulation or wet granulation are carried out depending upon stability of the drug with water molecules. Demand for pharmaceutical granulation equipment is expected to be driven by increase in research and production related to solid dosage forms across the world.

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Global Pharmaceutical Granulation Equipment Market: Drivers and Restraints

Increase in number of research laboratories, rise in R&D spending, and growing demand for advanced pharmaceutical drugs are the factors expected to boost the growth of the global pharmaceutical granulation equipment market. Moreover, technological advancements in the form of automation of granulation process, digital touchscreens, and increased production efficiency with reduced manpower are anticipated to fuel the growth of the global pharmaceutical granulation equipment market during the forecast period. However, high cost of equipment is likely to hamper the growth of the global pharmaceutical granulation equipment market.

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Global Pharmaceutical Granulation Equipment Market: Key Segments

The global pharmaceutical granulation equipment market can be segmented based on product type, application, end-user, and region. In terms of product type, the global market can be bifurcated into rapid mixer granulator and fluidized bed granulator. The rapid mixer granulator segment is expected to dominate the global pharmaceutical granulation equipment market owing to ease of installation, easy operational procedure, and availability in various sizes useful for research, pilot scale, and production purpose. The fluidized bed granulator segment is expected to grow at a rapid pace during the forecast period owing to improved characteristics of the granules produced by this equipment and modification of the equipment in the form of attached dryer which reduces the processing time. Based on application, the global pharmaceutical granulation equipment market can be classified into laboratory experiments, pilot batches scaling, and commercial scale manufacturing. In terms of end-user, the global market can be categorized into pharmaceutical research laboratories, pharmaceutical production plants, contract research & manufacturing organizations, and academic and research institutes. The pharmaceutical production plants segment is anticipated to account for major share of the global pharmaceutical granulation equipment market during the forecast period.

Geographically, the global pharmaceutical granulation equipment market can be segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America is expected to dominate the global pharmaceutical granulation equipment market. Rise in incidence of chronic diseases, increase in adoption of tablet, capsule, and dry powder dosage forms, surge in research in novel drug delivery systems are expected to drive the pharmaceutical granulation equipment market in the region. Europe is expected to be the second largest pharmaceutical granulation equipment market owing to presence of large number of pharmaceutical research and production facilities, increase in demand for high quality products, and stringent regulations controlling the quality of dosage forms. Asia Pacific is expected to be the most lucrative pharmaceutical granulation equipment market owing to increased outsourcing of research activities by leading players in the developed markets because of availability of skilled labor and low cost of research and manufacturing in countries such as China and India.

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Global Pharmaceutical Granulation Equipment Market: Key Players

Key players operating in the global pharmaceutical granulation equipment market include Nicomac Srl, Alexanderwerk AG, Karnavati Engineering Limited, Robert Bosch Packaging Technology GmbH, L.B. Bohle, Compression Components & Service, LLC, Fluid Air Systems, Romaco Group, and Vanguard Pharmaceutical Machinery.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications

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Hairy Cell Leukemia Treatment Market Size, Growth, Trends and 2025 Forecast Report

Hairy cell leukemia is an uncommon, chronic, slow-growing malignancy caused due to excessive production of B cells (lymphocytes) by the bone marrow. B cells are special types of white blood cells that play an important role in fighting infections in the body. Hairy cell leukemia got its peculiar name from a morphology trait it exhibits. The excess B cells in hairy cell leukemia grow abnormal extensions and look ‘hairy’. With the increase in the number of leukemia cells, the number of healthy white blood cells, red blood cells, and platelets in the body decreases significantly. Hairy cell leukemia comprises 2% of all the leukemia detected. Hairy cell leukemia is known to affect middle-aged males more than females. The exact cause of hairy cell leukemia is unknown; however, some studies suggest that DNA mutation in the memory B cell compartment leads to the start of malignancy. Hairy cell leukemia affects cells in the bone marrow, spleen, lymph nodes, and liver. It is a slow growing malignancy and gradually shows symptoms such as weakness, weight loss, fatigue, frequent infections due to lower immunity, and swelling of the spleen. The disease is incurable, but can be managed with proper treatment. The risk factors for hairy cell leukemia treatment include increased exposure to radiations, exposure to certain agricultural and industrial chemicals. People of Ashkenazi Jewish ethnicity are also found to be more susceptible to hairy cell leukemia than other population. The diagnostic approached to identify hairy cell leukemia treatment include physical examination for enlarged spleen and lymph nodes, blood tests, bone marrow biopsy, tumor markers presence test, and imaging studies such as CT scan.

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Global Hairy Cell Leukemia Treatment Market: Drivers and Restraints

The global hairy cell leukemia treatment market is anticipated to grow at a rapid pace during the forecast period owing to a number of factors. Hairy cell leukemia is found to affect individuals aged over 40 years. Hence, rapid rise in the global geriatric population is expected to increase incidence of hairy cell leukemia. High number of rural inhabitants who experience greater exposure to fertilizer chemicals and development of better and quicker diagnostic techniques are likely to increase the number of hairy cell leukemia treatment patients. However, lack of awareness about such malignancies and low efforts in research and development of novel treatment in hairy cell leukemia treatment is expected to restrain the market during the forecast period.

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Global Hairy Cell Leukemia Treatment Market: Key Segments

The global hairy cell leukemia treatment market can be segmented based on treatment type and region. In terms of treatment type, the hairy cell leukemia treatment market can be categorized into chemotherapy, biological treatment, and surgery. The chemotherapy treatment regime for hairy cell leukemia consists of two drugs: cladribine and pentostatin (Nipent). Biological treatment includes interferon and monoclonal antibody Rituximab (Rituxan). Surgical treatment is not common for hairy cell leukemia; however, removal of spleen or splenectomy is performed in few patients to provide relief from enlarged or ruptured spleen. Geographically, the global hairy cell leukemia treatment market can be segmented into North America, Europe, Asia Pacific, Middle East & Africa, and Latin America. North America is anticipated to account for the largest share of the global hairy cell leukemia treatment market due to presence of better health care infrastructure, strong national economics, and higher acceptance rate of innovative tools. The hairy cell leukemia treatment market in Europe is also expected to witness strong growth, attributed to high awareness about technological improvements and rise in spending on health care amenities. The hairy cell leukemia treatment market in developing nations in Asia Pacific is expected to grow at a rapid pace during the forecast period due to increase in awareness about various diseases and improving economic development.

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Global Hairy Cell Leukemia Treatment Market: Overview

Key players in the global hairy cell leukemia treatment market include Pfizer, Inc., Janssen Global Services, F. Hoffmann-La Roche Ltd., Emcure Pharmaceuticals, Dr. Reddy’s Laboratories, and Amgen, Inc.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Cardiac Catheterization MarketSize, Growth, Trends and 2025 Forecast Report

Cardiac catheterization can be defined as a procedure to test the functioning of the heart and is used to diagnose and treat cardiovascular conditions. During the process of cardiac catheterization, a catheter is inserted into the artery or vein, using which doctors perform diagnostic tests. Additionally, heart disease treatments such as coronary angioplasty can be performed using this process. The diagnostic tests usually performed using cardiac catheterization include biopsy, detection of congenital heart defects, right or left ventriculogram, angiogram, and hemodynamic assessment. The treatment procedures in which cardiac catheterization forms a part of the process include closure of holes in the heart, fixing congenital heart diseases, replacing heart valves, heart arrhythmia treatment, and angioplasty.

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Global Cardiac Catheterization Market: Drivers and Restraints

The global cardiac catheterization market is anticipated to record significant growth during the forecast period. This can be attributed to the rise in prevalence of cardiovascular diseases, increase in number of angiographic procedures, growing awareness among people, and favorable reimbursement scenario. Additionally, rise in prevalence of diabetes, increase in obesity among the population, and surge in demand for minimally invasive procedures fuel the growth of the market. Moreover, rise in number of cath labs globally drives the market. For instance, in India, the number of cath labs nearly doubled in the past five years to reach over 630 in 2015. Similarly, cardiac interventions in the country increased by 41% in 2015 as compared to 2014. According to the British Cardiac Society Guidelines, there has to be one diagnostic cardiac catheterization and angiography laboratory for a population of 450,000 to 600,000. France has the highest number of catheterization laboratories in Europe, accounting for 2.9 per 1 million people, as suggested by the British Cardiac Society Guidelines. However, the side effects associated with cardiac catheterization procedures and stringent regulatory environment for the approval of medical devices is likely hamper the growth of the market in the region.

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Global Cardiac Catheterization Market: Key Segments

The global cardiac catheterization market can be segmented based on product type, application, and region. Based on product type, the market can be categorized into angiographic balloon catheter, optical fiber scope, hexapolar balloon spacing, arterial embolectomy, and others. In terms of application, the global cardiac catheterization market can be classified into right heart catheterization, balloon angioplasty, coronary angiography, valve replacement, and others.

Geographically, the global cardiac catheterization market can be segmented into five major regions: North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America was the dominant market in terms of revenue in 2016 and the trend is anticipated to continue during the forecast period. This is attributed to rise in prevalence of cardiac diseases and well-established health care infrastructure in the region. Europe was the next major market for cardiac catheterization. However, the market in the region is anticipated to witness sluggish growth owing to slow economic recovery. The cardiac catheterization market in Asia Pacific is anticipated to grow at a rapid pace owing to increase in patient population, rise in government focus on enhancing health care facilities, and surge in disposable income of the people. The market in the region is anticipated to be driven by India and China during the forecast period due to high prevalence of several cardiac disorders in these countries. Moreover, rapidly improving awareness levels and cumulative healthcare sector development in these countries would also contribute towards cardiac catheterization market growth in these nations.

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Global Cardiac Catheterization Market: Key Players

Leading players operating in the global cardiac catheterization market include Medtronic plc, Boston Scientific Corporation, Terumo Corporation, GE Healthcare, Smith & Nephew, Johnson & Johnson, Cook Medical, Edwards Life Sciences, Abbott, B. Braun, C. R. Bard, and Teleflex Incorporated.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Transparency Market Research (TMR) is a U.S.-based provider of syndicated research, customized research, and consulting services. TMR’s global and regional market intelligence coverage includes industries such as pharmaceutical, chemicals and materials, technology and media, food and beverages, and consumer goods, among others. Each TMR research report provides clients with a 360-degree view of the market with statistical forecasts, competitive landscape, detailed segmentation, key trends, and strategic recommendations.

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Orphan Diseases Testing Market Report Explored in Latest Research 2017 – 2025

Development of molecular biology has transformed the diagnosis and treatment of diseases. Modern test methods, which are based on the detection of DNA and RNA, offer several advantages over traditional methods in the detection of diseases. The new procedures can detect viruses, bacteria, and genetic variations more accurately and rapidly. The continuous innovation in technology is useful to personalize health care and offer better treatment plans to patients. Genetic sequencing provides various types of technologies for the diagnosis of genetic disorders, some of the prominent technologies being RT-PCR, microarray sequencing, and next-generation sequencing.

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Availability of a wide range of molecular biology technologies for the diagnosis of diseases presents several choices depending on the cost of the test, capability of the testing method, and other parameters. These techniques are used for the diagnosis and testing of orphan diseases, also known as rare diseases. According to the criteria employed in the U.S., orphan diseases are rare diseases that affect less than 200,000 individuals in a population. According to the criteria applied in Europe, orphan diseases are rare diseases that affect less than five individuals among 10,000 people. At present, almost 5% of the world’s population is living with orphan diseases. According to various surveys, it is estimated that almost 75% of orphan diseases affect children and 30% of these patients die before attaining the age of five years. 80% of the orphan diseases are genetic in nature. Some of the orphan diseases are life-threatening. Approximately 700 orphan or rare diseases have been identified. Examples of orphan diseases include cystic fibrosis, Lou Gehrig’s disease, and Tourette’s syndrome. The diagnosis is generally carried out by genetic screening.

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Global Orphan Diseases Testing Market: Drivers and Restraints

Increasing technological advancements in genomics for the diagnosis and treatment of rare diseases and availability of patient-specific therapies for these diseases are estimated to fuel the global orphan diseases testing market during the forecast period. Moreover, increase in genetic screening for the diagnosis of hereditary disorders is likely to augment the Orphan Diseases Testing Market from 2017 to 2025. Emergence of new detection technologies in the genomics has enhanced the diagnosis of orphan diseases. Manufacturers are focusing on development of techniques such as PCR, imaging, and microarrays with greater depth of interaction (DoI). The need for new detection technologies in the testing of orphan diseases is due to ineffective methods of screening, which often give false-positive and false-negative results. Therefore, there is a need in achieving effective screening of the disease, which can be filled with innovative approaches that are more effective than the choices available currently.

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Global Orphan Diseases Testing Market: Key Segments

The global orphan diseases testing market can be segmented based on disease type, technology type, end-user, and region. Based on disease type, the Orphan Diseases Testing Market has been divided into cystic fibrosis, Lou Gehrig’s disease, and Tourette’s syndrome. Based on technology, the global orphan diseases testing market can be segmented into NGS platforms, RT-PCR, microarrays, and genetic analyzers. Next-generation sequencing is a DNA-sequencing technology, by which an entire human genome can be sequenced within a single day. Bioinformatics tools are used for analysis of the entire gene sequence for precise changes in a DNA sequence and hence, these tools are used in testing of orphan diseases. Based on end–user, the global orphan diseases testing market has been segmented into academic & research institutes, diagnostic centers, and others. Increasing R&D in the health care sector, which utilizes gene sequencing for the testing of orphan diseases, is expected to drive the orphan diseases testing market during the forecast period.

Based on region, the global orphan diseases testing market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global orphan diseases testing market in 2016. Dominance of the region is attributable to the presence of key players and rising research and development activities in the region. Rising awareness about orphan diseases and their testing in Asia Pacific is projected to fuel the orphan diseases testing market during the forecast period.

Global Orphan Diseases Testing Market: Key Players

Key players operating in the global orphan diseases testing market include Illumina, Inc., Thermo Fisher Scientific, Inc., and Bio-Rad Laboratories, Inc.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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